HOMA-IR Calculator
Medically reviewed by our Medical review board
Calculator Coming Soon
The interactive calculator will be available here soon.
The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) approximates insulin resistance using fasting insulin and fasting glucose.
It is a simple, noninvasive estimate after an overnight fast. Direct methods such as the euglycemic clamp are more definitive but are resource-intensive; HOMA-IR is widely used in research and as an adjunct in clinical discussion.
Formula
HOMA-IR = (Fasting insulin in μIU/mL) × (Fasting glucose in mg/dL) ÷ 405
When you enter SI units (pmol/L for insulin, mmol/L for glucose), values are converted using:
- Insulin: pmol/L = μIU/mL × 6
- Glucose: mmol/L = mg/dL × 0.0555
Interpreting results
There is no single universally accepted cutoff. Common references include:
- Values between about 2.0 and 3.0 in many U.S. clinical and research settings
- ≥2.5 often used (for example in NHANES analyses) to indicate insulin resistance
- Lower cutoffs (about 1.4–2.5) are sometimes discussed for Asian populations
HOMA-IR is not a diagnosis and should not replace clinical judgment. Discuss results with your healthcare provider.
- Use laboratory values from a fasting sample (about 8 hours overnight).
- Choose units: μIU/mL + mg/dL or pmol/L + mmol/L.
- Enter fasting insulin and fasting glucose.
- Tap Calculate to see your HOMA-IR score and a short interpretation.
Not reliable for: people with established diabetes on exogenous insulin, acute illness or stress, and some other groups (for example older adults or lean individuals in certain contexts). Results are assay- and population-dependent.